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Pediatric and systemic syndromes

Alagile syndrome

1:3210 visual cues1 clinical photo

In this image

Each number marks an object in the image and the finding it stands for.

  1. AlligatorAlagile syndrome
  2. DominoesAutosomal dominant inheritance
  3. Jagged scalesJAG1 mutation
  4. Wide headCharacteristic facial features
  5. White eye ringPosterior embryotoxon
  6. Liver dripsIntrahepatic cholestasis
  7. Yellow eyeJaundice
  8. Speckled islandPigmentary retinopathy
  9. Abnormal heartCongenital heart disease
  10. Butterfly scalesButterfly vertebrae; Bony abnormalities
  11. ReviewEvery marker, in order

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Clinical image credits

Openly licensed photographs used in this lesson, with what was changed.

  1. Vishal V. Bhende, Hardil P. Majmudar, Tanishq S. Sharma, Sohilkhan R. Pathan, Deepakkumar V. Mehta (2021). Nonhepatic Alagille Syndrome Associated With Predominant Cardioskeletal Anomalies: A Rare Case.

    CC BY 3.0Article

    Exact rectangular crop [0, 0, 750, 733] from 750 × 733 publisher figure. Decoded RGB pixels preserved; no enhancement, arrows, retouching or upscaling.