
Retina and optic nerve
Best disease
1:417 visual cues1 clinical photo
In this image
Each number marks an object in the image and the finding it stands for.
- BEST bannerBest disease
- Parent with dominoAutosomal dominant inheritance
- VMD2 family crestVMD2 gene affected
- Child + chartPresents in childhood; Good visual acuity maintained
- Egg yolk to scrambled eggVitelliform lesion to atrophic appearance
- Red ball binCNVM in 20% of patients
- ERG / EOGERG normal; EOG always abnormal
- ReviewEvery marker, in order
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Clinical image credits
Openly licensed photographs used in this lesson, with what was changed.
Lucia Ambrosio, Tatiana Perepelkina, Abdelrahman M. Elhusseiny, Anne B. Fulton, Jose Efren Gonzalez Monroy (2025). Advancing Insights into Pediatric Macular Diseases: A Comprehensive Review.
Exact rectangular crop [382, 34, 740, 295] from 746 × 1038 publisher figure. Decoded RGB pixels preserved; no enhancement, arrows, retouching or upscaling.
