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Retina and optic nerve

Gyrate atrophy

2:0311 visual cues1 clinical photo

In this image

Each number marks an object in the image and the finding it stands for.

  1. GyroscopeGyrate atrophy
  2. Candy cupAutosomal recessive inheritance
  3. OatsOAT deficiency
  4. OwlsMarkedly elevated plasma ornithine
  5. FenceScalloped chorioretinal atrophy
  6. NightNyctalopia
  7. GlassesHigh myopia
  8. CrescentPSC cataract
  9. ERGProgressive ERG reduction
  10. Bee + 6Vitamin B6 supplementation
  11. PretzelsDietary arginine restriction
  12. ReviewEvery marker, in order

Transcript

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Clinical image credits

Openly licensed photographs used in this lesson, with what was changed.

  1. Palmer E, Stepien KM, Campbell C, Barton S, Iosifidis C, Ghosh A, Broomfield A, Woodall A, Wilcox G, Sergouniotis PI, Black GC (2023). Clinical, biochemical and molecular analysis in a cohort of individuals with gyrate atrophy. Orphanet Journal of Rare Diseases 18:265. Figure 1A, left colour fundus photograph.

    CC BY 4.0Article

    Cropped to the left colour panel; no other visual changes.

    Exact changes

    Exact rectangular crop [0, 0, 898, 545] from the 1770 × 1730 publisher JPEG. Retains the complete left colour fundus photograph from Figure 1A, its original A label and narrow original white margins. Excludes the right colour photograph and all Figure 1B and 1C panels. Losslessly encoded as RGB PNG with decoded RGB pixels identical to the corresponding original JPEG crop. No retouching, recoloring, enhancement, added annotations, arrows or upscaling.