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Cornea

Granular corneal dystrophy type 1

1:457 visual cues2 clinical photos

In this image

Each number marks an object in the image and the finding it stands for.

  1. Granular snowflakesGranular corneal dystrophy type 1
  2. FBI agentTGFBI gene mutation
  3. Clear spacesGranular deposits with clear spaces between lesions
  4. Clearing the edgeLesions do not extend limbus to limbus
  5. Red mason jarHyaline material stains red with Masson trichrome
  6. Ice holesRecurrent corneal erosions possible
  7. BatonRod-shaped fibers on electron microscopy
  8. ReviewEvery marker, in order

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Clinical image credits

Openly licensed photographs used in this lesson, with what was changed.

  1. Eduardo Gayger Müller, José Álvaro Pereira Gomes, Walton Nosé, Ricardo Menon Nosé (2018). Persistence of granular corneal dystrophy type-1 deposits in the predescemetic layer after big-bubble deep anterior lamellar keratoplasty.

    CC BY 4.0Article

    Exact rectangular crop [0, 0, 900, 881] from 900 × 881 publisher figure. Decoded RGB pixels preserved; no enhancement, arrows, retouching or upscaling.

  2. Eduardo Gayger Müller, José Álvaro Pereira Gomes, Walton Nosé, Ricardo Menon Nosé (2018). Persistence of granular corneal dystrophy type-1 deposits in the predescemetic layer after big-bubble deep anterior lamellar keratoplasty.

    CC BY 4.0Article

    Exact rectangular crop [0, 0, 900, 736] from 900 × 736 publisher figure. Decoded RGB pixels preserved; no enhancement, arrows, retouching or upscaling.