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Cornea

Meesmann corneal dystrophy

MECD

1:236 visual cues1 clinical photo

In this image

Each number marks an object in the image and the finding it stands for.

  1. Mice homeMeesmann corneal dystrophy
  2. Cart toyKeratin mutation: KRT12
  3. Baby mousePresents in infancy
  4. Window bubblesTiny, uniform epithelial microcysts
  5. Peculiar blobPeculiar substance on electron microscopy
  6. Smiling miceOften asymptomatic; Good visual acuity
  7. ReviewEvery marker, in order

Transcript

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Clinical image credits

Openly licensed photographs used in this lesson, with what was changed.

  1. Víctor Charoenrook, Raquel Larena, Álvaro Ferragut-Alegre, Alix De Faria, Rebeca Valero, Mònica Martí-Orpinell, Gemma Julio, Rafael I. Barraquer (2026). Meesmann Corneal Dystrophy with Epithelial Basement Membrane Abnormalities: Clinical and Genetic Analysis of Two Families with Novel and Known Mutations in KRT3 and KRT12.

    CC BY 4.0Article

    Exact rectangular crop [1028, 0, 2035, 680] from 3064 × 1652 publisher figure. Decoded RGB pixels preserved; no enhancement, arrows, retouching or upscaling.